Grayanotoxane-5,6,10,14,16-pentol,2,3-epoxy-, 6-acetate, (2b,3b,6b,14R)- (9CI) - Names and Identifiers
Name | Rhodojaponin II
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Synonyms | Rhodojaponin Ⅱ Rhodojaponin II (14R)-2β,3β-Epoxygrayanotoxane-5,6β,10,14,16-pentol 6-acetate Grayanotoxane-5,6,10,14,16-pentol,2,3-epoxy-, 6-acetate, (2b,3b,6b,14R)- (9CI) Grayanotoxane-5,6,10,14,16-pentol, 2,3-epoxy-, 6-acetate, (2β,3β,6β,14R)- (9CI)
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CAS | 26116-89-2
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EINECS | 300-009-1 |
Grayanotoxane-5,6,10,14,16-pentol,2,3-epoxy-, 6-acetate, (2b,3b,6b,14R)- (9CI) - Physico-chemical Properties
Molecular Formula | C22H34O7
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Molar Mass | 410.51 |
Density | 1.36±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 294.5-296℃ |
Boling Point | 569.4±50.0 °C(Predicted) |
Solubility | Soluble petroleum ether, chloroform, ethyl acetate and other organic solvents, insoluble in water. |
Appearance | White crystal |
pKa | 13.27±0.70(Predicted) |
Storage Condition | 2-8℃ |
MDL | MFCD01714941 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Rhododendron molle G. Don, a plant of the genus Rhododendron of the family Rhododendron. |
Grayanotoxane-5,6,10,14,16-pentol,2,3-epoxy-, 6-acetate, (2b,3b,6b,14R)- (9CI) - Introduction
Boatoxin II (or "agent II") is a natural toxin produced by bacteria. It is a fat-soluble toxin with the chemical structure of polycyclic nucleotides of deoxyribonucleic acid (DNA).
Boatoxin II is widely used in laboratory research and biotechnology. It has the activity of inhibiting nucleic acid synthesis and can be used as a tool for gene expression regulation. Due to its highly specific and powerful inhibitory effect, it is widely used to study processes such as DNA replication, transcription and translation.
The preparation method of sheep flower toxin II is mainly obtained by cultivating toxin-producing strains (such as Escherichia coli). These bacteria have been genetically engineered so that they can produce cargotoxin II in large quantities. Then, after bacterial culture and subsequent purification and refining steps, the pure sheep flower toxin II is finally obtained.
it should be noted that sheep flower toxin II is highly toxic and should be operated in strict accordance with laboratory safety procedures. Wear appropriate protective equipment to avoid contact with skin, inhalation or ingestion. When in use, should be sealed storage, avoid leakage and evaporation. In addition, the treatment and disposal of waste should pay attention to environmental protection requirements, in accordance with the relevant laws and regulations.
In General, cargotoxin II is an important biological research tool, but strict safety procedures need to be followed during use to ensure the safety of laboratories and operators.
Last Update:2024-04-09 21:04:16